Brian Kennedy
Professor at the National University of Singapore. Former president of the Buck Institute for Research on Aging in California.
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Human longevity trials and aging with Dr Brian Kennedy (8:08) Sep 15, 2022. Study of AKG in humans [Aging, Nov 30, 2021] showed an 8 year decrease in biological age after 7 months of use. DNA methylation testing before and after. AKG in cells goes down with age. AKG involved in 700 reactions in the cell. People biologically older than their chronological age responded best. AKG conjugated with calcium and time released. Different male and female formulas. Looking for different AKG combinations.
SPERMIDINE – A Natural & Promising Molecule | Dr Brian Kennedy Interview Clips (2:43) Sep 10, 2022. A natural molecule you get through diet, goes down with age, activates autophagy. Extends life in mice on a high fat diet. May be more beneficial for people with unhealthy diets. Do small studies of different interventions.
Professors Brian Kennedy and Andrea Maier on ageing and healthy longevity (7:15) Sep 7, 2022. Aging is the major driver of chronic diseases. Want to intervene while people are healthy to extend healthspan. Personalized interventions for Chinese, Indian, and Malayan populations. Outpatient clinic next year at Alexandra Hospital. Can extend lifespan by 30 or even 50% in mice. Aim is health care rather than sick care.
AKG & Gemfibrozil – 2 Promising Geroprotectors For Slowing Aging | Dr Brian Kennedy Interview Clips (2:41) Aug 17, 2022. Possible geroprotectors: melatonin, carnosine, metformin, rapamycin, NMN (Wikipedia). 20-50 geroprotectors. Human trials to see which ones work. AKG (alpha ketoglutarate) reduces frailty. Gemfibrozil to decrease triglycerides and cholesterol.
Brian Kennedy – 2 mins (1:53) Jul 20, 2022. Easier to keep you healthy than to repair sickness. Can extend mouse lifespan by 35%. 6-month studies in Singapore on healthy people 45 to 65 using biomarkers. Imagine reducing biological age by 5 years.
Optimize Our VITAMIN LEVELS Can Have HUGE IMPACT On AGING | Dr Brian Kennedy Interview Clips (4:29) May 31, 2022. Small pills with many ingredients can have only small amounts of any one thing. Vitamin A. Finding the optimal dose of vitamins for each individual could have a huge impact on aging.